Iris Rajman: search on Z-Library

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1

Cytochrome P450 2C19*2 polymorphism in patients with stable coronary heart disease and risk for secondary cardiovascular disease events: results of a long-term follow-up study in routine clinical care

Rothenbacher, Dietrich, Hoffmann, Michael M, Breitling, Lutz P, Rajman, Iris, Koenig, Wolfgang, Brenner, Hermann

Journal:

BMC Cardiovascular Disorders

Year:

2013

Language:

english

File:

PDF, 236 KB

english, 2013

2

PK/PD modelling and simulations: utility in drug development

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 126 KB

english, 2008

3

The oxidation hypothesis of atherosclerosis

Iris Rajman, Martin Kendall, Robert Cramb

Journal:

Year:

1994

Language:

english

File:

PDF, 330 KB

english, 1994

4

Inhibitory effects of low-density lipoproteins from men with type II diabetes on endothelium-dependent relaxation

Karen L. McNeill, Luigi Fontana, David L. Russell-Jones, Iris Rajman, James M. Ritter, Philip J. Chowienczyk

Journal:

Journal of the American College of Cardiology

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

5

A Risk-Benefit Assessment of Celiprolol in the Treatment of Cardiovascular Disease

Dr Martin J. Kendall,Iris Rajman

Journal:

Year:

1994

Language:

english

File:

PDF, 1.30 MB

english, 1994

6

Safety and tolerability of serelaxin, a recombinant human relaxin-2 in development for the treatment of acute heart failure, in healthy Japanese volunteers and a comparison of pharmacokinetics and pharmacodynamics in healthy Japanese and Caucasian populat

Dahlke, Marion, Ng, Dik, Yamaguchi, Masayuki, Machineni, Surendra, Berger, Sergej, Canadi, Jasna, Rajman, Iris, Lloyd, Peter, Pang, Yinuo

Journal:

Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 658 KB

english, 2015

7

Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol

Hsiao, Hsiu-ling, Langenickel, Thomas Heiko, Greeley, Michael, Roberts, John, Zhou, Wei, Pal, Parasar, Rebello, Sam, Rajman, Iris, Sunkara, Gangadhar

Journal:

Clinical Pharmacology in Drug Development

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

8

Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects

Gan, Lu, Jiang, Xuemin, Mendonza, Anisha, Swan, Therese, Reynolds, Christine, Nguyen, Joanne, Pal, Parasar, Neelakantham, Srikanth, Dahlke, Marion, Langenickel, Thomas, Rajman, Iris, Akahori, Mizuki,

Journal:

Clinical Pharmacology in Drug Development

Year:

2015

Language:

english

File:

PDF, 605 KB

english, 2015

9

Pharmacokinetics of serelaxin in patients with hepatic impairment: a single-dose, open-label, parallel group study

Kobalava, Zhanna, Villevalde, Svetlana, Kotovskaya, Yulia, Hinrichsen, Holger, Petersen-Sylla, Marc, Zaehringer, Andreas, Pang, Yinuo, Rajman, Iris, Canadi, Jasna, Dahlke, Marion, Lloyd, Peter, Halabi

Journal:

British Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

10

The effect of LCZ696 on amyloid-β concentrations in cerebrospinal fluid in healthy subjects

Langenickel, Thomas H., Tsubouchi, Chiaki, Ayalasomayajula, Surya, Pal, Parasar, Valentin, Marie-Anne, Hinder, Markus, Jhee, Stanford, Gevorkyan, Hakop, Rajman, Iris

Journal:

British Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.30 MB

english, 2015

11

Single therapeutic and supratherapeutic doses of sacubitril/valsartan (LCZ696) do not affect cardiac repolarization

Langenickel, Thomas H., Jordaan, Pierre, Petruck, Jesika, Kode, Kiran, Pal, Parasar, Vaidya, Soniya, Chandra, Priya, Rajman, Iris

Journal:

European Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

12

Effect of renal function on the pharmacokinetics of LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor

Ayalasomayajula, Surya P., Langenickel, Thomas H., Jordaan, Pierre, Zhou, Wei, Chandra, Priyamvada, Albrecht, Diego, Pal, Parasar, Rajman, Iris, Sunkara, Gangadhar

Journal:

European Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 448 KB

english, 2016

13

Assessment of Drug–Drug Interaction Potential Between Atorvastatin and LCZ696, A Novel Angiotensin Receptor Neprilysin Inhibitor, in Healthy Chinese Male Subjects

Ayalasomayajula, Surya, Pan, Wei, Han, Yi, Yang, Fan, Langenickel, Thomas, Pal, Parasar, Zhou, Wei, Yuan, Yaozong, Rajman, Iris, Sunkara, Gangadhar

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2016

Language:

english

File:

PDF, 605 KB

english, 2016

14

Evaluation of Methods for Improving Precision of Blood Pressure Measurements in Phase I Clinical Trials

Terra, Steven G., Blum, Robert A., Wei, Greg C., Lew, Robert A., Digenio, Andres G., Rajman, Iris, Kazierad, David J.

Journal:

Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004

15

Pergolide

Thalamas, Claire, Rajman, Iris, Kulisevsky, Jaime, Lled??, Alberto, Mackie, Alison E, Blin, Olivier, Gillespie, Todd A, Seger, Mary, Rascol, Olivier

Journal:

Clinical Neuropharmacology

Year:

2005

Language:

english

File:

PDF, 193 KB

english, 2005

16

Effects of age and sex on the pharmacokinetics of LCZ696, an angiotensin receptor neprilysin inhibitor

Gan, Lu, Langenickel, Thomas, Petruck, Jesika, Kode, Kiran, Rajman, Iris, Chandra, Priya, Zhou, Wei, Rebello, Sam, Sunkara, Gangadhar

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 262 KB

english, 2016

17

African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development

Rajman, Iris, Knapp, Laura, Morgan, Thomas, Masimirembwa, Collen

Journal:

Year:

2017

Language:

english

File:

PDF, 948 KB

english, 2017

18

Introducing Project Africa GRADIENT

Rajman, Iris, Pasqua, Oscar Della

Journal:

Drug Discovery Today

Year:

2019

File:

PDF, 273 KB

2019

19

New paradigm for expediting drug development in Asia

Rajman, Iris, Hirano, Masaru, Honma, Wataru, Zhao, Sylvia

Journal:

Drug Discovery Today

Year:

2020

Language:

english

File:

PDF, 202 KB

english, 2020

20

Genetic Diversity in Drug Transporters: Impact in African Populations

Rajman, Iris, Knapp, Laura, Hanna, Imad

Journal:

Clinical and Translational Science

Year:

2020

File:

PDF, 1.70 MB

2020